CAR-T Cell Transcriptomics
CAR-T cell therapy is hailed as one of the greatest cancer therapy breakthroughs of the last decade. But we still don't know a lot about what makes some CARs better at clearing cancer and why some CARs are more durable. Here we did RNA-seq analysis on both CD4 and CD8 CAR T cells with 3 different constructs to analyze their differences.
RNA-Seq, Data Mining, DE, Pathway Analysis, Immune Profiling
Avg. Hours / Week
Wes Wilson / Mike Milone
Publication if successful?
Trainee authorship criteria (if applicable)
NOTE: You can also complete the python versions of these trainings if you want (RNA-Seq should still be done with R). Additionally, preference will be given to those who have knowledge about scRNA-Seq, which you can get from the BIG scRNA-Seq workshop: https://www.bigbioinformatics.org/intro-to-scrnaseq