STAG2 and R-loops in the epigenome
In a recent study, our group demonstrated that STAG2 binds R-loops and protects them from degradation. We also found evidence that STAG2 may perform this function at enhancers to preserve their activity. This study combines multiple HTS datasets from public and private sources to characterize the R-loop/STAG2 interaction at enhancers.
RNA-Seq, ChIP-Seq, Data Integration
Avg. Hours / Week
Alex Bishop, D.Phil.
Aparna Gorthi & Henry Miller
Publication if successful?
Trainee authorship criteria (if applicable)
Trainees who contribute meaningfully to the project will be listed as co-authors. E.g., performing an entire core analysis or developing a core component of project software.