R-loops and Splicing

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Description

Analysis of gene expression and DRIP-Sequencing datasets to answer: (1) How does splicing deficiency in Ewing sarcoma impact R-loops? (2) Is pushing the defficiency further a valid treatment approach?

R

RNA-Seq, ChIP-Seq, Data Integration

Project Stage

Late

Avg. Hours / Week

6

Project Provider

Alex Bishop, D.Phil.

Commitment (Months)

6

Spots Open

1

Project Lead

Liesl Lawrence & Henry Miller

Publication if successful?

Yes

Trainee authorship criteria (if applicable)

Trainees who contribute meaningfully to the project will be listed as co-authors. E.g., performing an entire core analysis or developing a core component of project software.

Required Skill Assessments

ChIP-Seq Analysis

RNA-Seq Analysis

R for Data Science

R Programming