Closed / Completed Projects
Sep 4, 2022
Analysis of genomic variants in schwannomatosis (COMING SOON)
Development of a pipeline to characterize and prioritize genomic variants in schwannomatosis. Prioritized variants will be used to design additional analyses and the pipeline may be applied to genomic datasets from related rare diseases.
Variant analysis, Variant interpretation, Nextflow pipelines
R-loops and the Aging Epigenome
Analysis of the role of R-loops in promoting epigenomic aging via enhancer dysregulation.
RNA-Seq, ChIP-Seq, scRNA-Seq, Data Integration, Data Mining, Snakemake, Linux
R-loops across the CCLE (Merck Project)
R-loops are important but poorly understood. This project uses dozens of cancer cell lines to determine what are the genomic, epigenomic, and transcriptomic impacts of R-loops.
RNA-Seq, Data Integration, Data Mining