R-loops are vitally important but poorly understood. By integrating dozens of datasets across multiple studies, we aim develop a systems model of R-loop biology. This will include activities such as uncovering and characterizing conserved vs transient R-loops and finding R-loops that associate with particular biological conditions.
RNA-Seq, ChIP-Seq, Data Integration, Data Mining
Avg. Hours / Week
Alex Bishop, D.Phil.
Publication if successful?
Trainee authorship criteria (if applicable)
Trainees who contribute meaningfully to the project will be listed as co-authors. E.g., performing an entire core analysis or developing a core component of project software.